In vitro anti-proliferative and anti-angiogenic activities of thalidomide dithiocarbamate analogs

Anti-Angiogenic and Anti-Proliferative Effects of Physalis Alkekengi Hydroalcholic Extract on Breast Cancer in Mice

Background & Objective: The Physalis alkekengi is a herbaceous plant belonging to Solanaceae family. According to research, this plant can help inhibit cancer cell growth. Materials & Methods: In this study, the extract of Physalis alkekengi was used to suppress angiogenesis in Balb/c mice. First, the MC4L2 cells were injected in the mice breastbone and the tumor began to grow in this area, th...

The Anti-Proliferative and Anti-Angiogenic Effect of the Methanol Extract from Brittle Star

Background: Anti-angiogenic therapy is a crucial step in cancer treatment. The discovery of new anti-angiogenic compounds from marine organisms has become an attractive concept in anti-cancer therapy. Because little data correlated to the pro- and anti-angiogenic efficacies of Ophiuroidea, which include brittle star, the current study was designed to explore the anti-angiogenic potential of bri...

the anti-proliferative and anti-angiogenic effect of the methanol extract from brittle star

background: anti-angiogenic therapy is a crucial step in cancer treatment. the discovery of new anti-angiogenic compounds from marine organisms has become an attractive concept in anti-cancer therapy. because little data correlated to the pro- and anti-angiogenic efficacies of ophiuroidea, which include brittle star, the current study was designed to explore the anti-angiogenic potential of bri...

anti-proliferative and apoptotic activities of chrysin in neuroblastoma cells

Is thalidomide a true anti-angiogenic molecule in multiple myeloma?

In the March issue of this journal Patrizia Tosi and Michele Cavo reported about the use of thalidomide in multiple myeloma (MM).1 They underline that the mechanisms of action of thalidomide are poorly defined yet. Among them (some of which are only hypothesized2), one of the most controversial is whether thalidomide acts as an anti-angiogenic. The use of thalidomide in patients with endstage r...